Time Speaker/Session Introduction
07:30 AM Symposium Registration Opens
08:45 AM Welcome to the Symposium – Opening Remarks: Raj Rajur, CreaGen Inc. Chair, Medicinal Chemistry NESACS Mark Ashwell, Nimbus Therapeutics
Morning Session Chair: Paul Greenspan, Takeda
09:00 AM Phil Baran, Scripps Research Institute
Title: Translational Chemistry
Introduced by Andrew Scholte (Sanofi)
09:50 AM David Liu, Harvard University
Title: Base editing: Chemistry on individual nucleotides in the genome of living cells
Introduced by Lisa Marcaurelle (GSK)
10:40 AM Networking break in the Exhibition Hall with refreshments & food
11:10 AM Margaret Chu-Moyer, Amgen
Title: Innovative Modalities in the Fight Against Cancer: Drugging the "Undruggable" and Curing the Incurable
Introduced by Blaise Lippa (Morphic)
12:00 PM – 02:00 PM Lunch Break
Afternoon Session Chair: Brian Aquila (Alkermes)
02:00 PM Larry Hamann, Celgene
Title: Expanding the Druggable Genome through Cereblon-Mediated Protein Degradation
Introduced by Mark Ashwell (Nimbus Therapeutics)
02:50 PM Ann Weber, Kallyope
Title: From JANUVIA (Sitagliptin) to MARIZEV (Omarigliptin): a Once Weekly DPP-4 Inhibitor for the Treatment of Diabetes
Introduced by Scott Edmonson (AstraZeneca)
03:40 PM Networking break in Exhibition Hall with refreshments & food
04:10 PM
Keynote Presentation: Prof. Jack Szostak, Nobel Laureate, MGH, Harvard Medical School
Title: The surprising chemistry of nonenzymatic RNA replication
Introduced by Brian Aquila, Alkermes, Inc
05:00 PM Closing remarks and opening of Social Event - NESACS Dan Elbaum (QurAlis)
05:00 PM – 06:00 PM Social Networking with refreshments & food in the Exhibition Hall